Mast cells have been around since before the adaptive immune system developed in mammals 500 million years ago. But for such an old cell, we know relatively little about what it does. One of the first ...

Q: My doctor thinks my mast cells are activating inappropriately and may be causing many of the symptoms I periodically have. Please tell me more about this condition. A: Mast cells are an important ...

Certain immune cells backstab their cellular coworkers during allergic reactions. Mast cells, the security patrols of the immune system, can trigger allergic inflammation when they run into unfamiliar ...

Jeanetta has been feeling poorly and never knew why until recently. Now 75, she's suffered for years with intermittent headaches, muscle and joint pain, fatigue and sometimes even broke out in rashes ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Mast cells are pivotal effectors in immune responses, acting as both sentinels and mediators in allergic and inflammatory processes. Their ability to rapidly degranulate and release a myriad of ...

Chronic urticaria (CU) is a dermatological condition characterized by recurrent wheals (hives), angioedema (deep tissue swelling), or both, persisting for over 6 weeks. 1 Unlike acute urticaria, which ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

Celldex Therapeutics (NASDAQ:CLDX) executives used an appearance at H.C. Wainwright’s annual Inflammation and Skin Disease ...

Systemic mastocytosis (SM) is a rare blood disorder in which the body produces too many mast cells. Part of the immune response, mast cells are a type of white blood cell that releases histamine in ...

Many patients who call requesting an initial psychiatric consultation are suffering from a common condition known as mast cell activation syndrome (MCAS). MCAS can present with extremely diverse ...