A new study shows that targeting key epigenetic proteins may permanently switch off cancer genes. Scientists at Monash University, working with Harvard University, report they have found a way to ...

The role of epigenetic mechanisms, such as DNA or RNA methylation, histone modifications, nucleosome changes, and non-coding RNAs in cancer has gained increasing interest in recent studies. The ...

The KLF5 gene fuels growth spreading pancreatic cancer not by acquiring abnormal changes in the cancer cells' DNA but by altering chemical changes and organization of DNA.

Monash University researchers, in collaboration with Harvard University, have discovered how to permanently "switch off" cancer-causing genes, revealing a new approach to cancer treatment. The ...

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a new study. The preclinical research ...

Cellular findings show Telomir-Zn modulates intracellular metal balance linked to oxidative stress, mitochondrial dysfunction, DNA methylation instability, and genomic integrity-without relying on ...

Researchers at the University of Basel and the University Hospital of Basel report a process that helps breast cancer cells implant themselves in certain places in the body. The findings suggest a way ...

Combined epigenetic and immune checkpoint therapy altered the tumour microenvironment in platinum-resistant ovarian cancer.

In this Teach Me in 10, Dr Ben Greulich, Assistant Professor of Biology at Mercer University, clarifies how epigenetic ...

Researchers have revealed a reason why endocrine resistance develops in breast cancers and how to potentially treat it in patients. Endocrine resistance -- a major cause of breast cancer deaths -- can ...

DNA mutations in oncogenes and tumor suppressor genes drive tumorigenesis, but epigenetic modifications, such as DNA methylation, take center stage in a new era of cancer research. 1 In a study ...

The role of epigenetic mechanisms in cancer has gained interest in recent studies. The reversible nature of epigenetic changes on genomic DNA and histones holds promise for the development of ...