The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Researchers at Kumamoto University have developed a highly sensitive blood test that can detect subtle differences in how easily blood begins to clot, offering new possibilities for tailoring ...

As people age they become more prone to blood clotting diseases, which can be caused when blood platelets clump together. This clumping can lead to strokes and cardiovascular disease. For decades, ...

Blood clotting can lead to life-threatening heart attacks and strokes, and current treatments can lead to excessive bleeding and other worrisome side effects. But researchers now say they've found a ...

Disseminated intravascular coagulation (DIC) is a severe systemic disorder characterised by paradoxical clotting and bleeding, commonly triggered by sepsis – the body’s dysregulated response to ...

An in-depth review article describing coronavirus disease 2019 (COVID-19)-related coagulopathy has recently been published in the journal Nature Reviews Immunology. Hyperinflammation and ...

A growing body of evidence indicates that coagulation factors may exhibit not only prothrombotic but also proatherogenic effects. Recent years have yielded numerous animal studies demonstrating that ...

Inflammatory bowel disease, in which the immune system attacks the gut, is a painful chronic condition that affects three million Americans. Rates of IBD are rising, and there's currently no cure. IBD ...

Researchers have discovered the blood clotting and immune protein pathways that are activated in severe cases of COVID-19 in children, paving the way for earlier diagnosis and more targeted treatments ...