Three-dimensional image of a developing limb bud generated using LimbLab. It shows where key genes are active during early limb formation. Sox9 (magenta) marks the cells that will become cartilage and ...

This figure illustrates that TBX4 is crucial for mammalian limb development during the embryonic stage. It activates FGF10 within the mesoderm and interacts with β-catenin in the Wnt pathway, driving ...

When a salamander loses a leg, it grows back. When a human loses a finger, scar tissue fills the gap. The difference has ...

Some amputated limbs heal into scars. Others begin building themselves back. That split has long sat at the center of regeneration research. Salamanders and frog tadpoles can regrow lost limbs, while ...