Acute kidney injury (AKI) is associated with a poor prognosis, and no effective treatment has been established to date. Understanding the mechanisms that prevent the progression of AKI is crucial. In ...

Macrophages and other immune cells are the natural frontline immune warriors of our body, defending the body against invading pathogens and cancer cells. Yet despite their innate "combat" capabilities ...

An enzyme that controls the maturation and long-term survival of immune cells called macrophages has been discovered, with implications for research on aging and inflammatory disease. Virtually all ...

Macrophages, as integral components of the immune system, exhibit diverse roles due to their ability to assume various ...

Scientists have uncovered a powerful genetic switch that helps some of the body’s most important immune cells grow up properly and keep our organs healthy. The switch, called MafB, guides immature ...

Researchers at the University of Liège have identified a key genetic regulator that enables macrophages to reach full maturity and preserve the health of our organs. The MafB factor, a veritable ...

Researchers Sumika Kato, Takeo Kubo, and Taro Fukazawa of the University of Tokyo have discovered that c1qtnf3, a secreting factor, namely a protein molecule that is secreted by a cell and influences ...