Mast cells are tissue-resident immune cells that play a key role in inflammation and allergy. Here we show that interaction of mast cells with antibody-targeted cells induces the polarized exocytosis ...

TNF-encapsulating particles traverse to draining lymph nodes and boost production of vaccine-induced antibodies. Scientists report on the development of cytokine-loaded nanoparticles that act as lymph ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Groundbreaking research from Duke-NUS offers new hope to millions with asthma and severe food allergies, signalling a new strategy for the prevention of life-threatening reactions Scientists at ...

The itching, redness and swelling of an allergic reaction are caused by mast cells — the vigilant first responders of the immune system that spring into action with histamine-filled granules in ...

A rare set of immune diseases called clonal mast cell activation disorders (cMCADs) may be associated with strong immunity to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is ...