Neprilysin, one of a handful of proteases known to degrade amyloid-β (Aβ), might seem an attractive therapeutic for Alzheimer disease (AD)—until you consider the difficulties of administration. Direct ...
The current issue of Neuron contains a scientific debate that bears watching. It is about one of the great mysteries of amyloid-β precursor protein (APP), that is, its physiological role. Scientists ...
Barcelona, Spain – 26 Aug 2022: Sacubitril/valsartan does not change cognitive function, compared with valsartan, in patients with heart failure and mildly reduced or preserved ejection fraction, ...
Neprilysin inhibitors offer a new target for therapeutics. Neprilysin is an enzyme that degrades endogenous natriuretic peptides. [1] These peptides are secreted during times of fluid overload when ...
Researchers at Karolinska Institutet in Sweden and the RIKEN Center for Brain Science in Japan have identified two receptors in the brain that control the breakdown of amyloid beta, a substance that ...
New York (March 25, 2026) – Researchers presenting at the American Geriatrics Society (AGS) Virtual Annual Scientific Meeting (#AGS26), taking place April 30 th – May 2 nd (pre-conference days Monday, ...
Dr. Edward Dempsey and colleagues of the University of Colorado observed that neprilysin protects against PHTN. Patients with pulmonary hypertension, an increase in pressure in blood vessels in the ...
See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Scientists have identified a potential new target for treating ...
In women, invasive breast cancer is the second most common cancer and the second cause of cancer-related death. Therefore, identifying novel regulators of breast cancer invasion could lead to ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results