Validated, tissue-specific library enables customisable and controllable liver-targeted gene expression with high specificity and minimal off-target activity in muscle tissue ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a number of ...

Researchers say the deep learning model may help to create leads for new cancer diagnostics, patient stratification, and future therapies.

In this study, researchers analyzed large ASD whole genome sequencing data and found that promoter de novo mutations in TADs containing ASD genes were specifically associated with the disease.