WEHI researchers have discovered a never-before-seen mechanism our bodies use to regulate sugar, in findings that rewrite the ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, ...

Researchers at WEHI have discovered that ubiquitin, a protein best known for tagging damaged proteins, can also attach to glycogen and regulate its breakdown. Using a new technique called ...

Ubiquitin is a small protein consisting of 76 amino acids that binds to lysine residues of substrates, usually by a combination of three enzymes: a ubiquitin-activating enzyme (E1, two types), a ...

Mechanisms associated with the genesis of cancer stem cell stemness, such as oxidative stress, tumor metastasis and recurrence, hypoxia induction, and tumor invasion. Genes & Diseases publishes ...