Histone post-translational modifications (PTMs) have numerous crucial roles in genome management, in part by recruiting or stabilizing chemical or structural modification activities. These recruited ...
Bromodomains (BRDs) are evolutionarily conserved protein–protein interaction modules. Structure-based alignments have clustered human BRDs into eight distinct families. BRD modules share a conserved ...
Spermidine and its derivative, hypusinated eIF5A, are essential for the growth of Saccharomyces cerevisiae. Very low concentrations of spermidine (10⁻⁸ M) are sufficient for the growth of S.
Researchers from CIIMAR and the University of Helsinki have discovered a new biochemical modification in natural ...