Senescent CD8+ T cells impair CAR T therapy by reducing cell growth, migration, and tumor killing, with gene signatures ...

Kidney damage is a serious complication affecting individuals with lupus, an autoimmune disease where immune B cells ...

T-cell profiles derived from blood and renal biopsy may be novel biomarkers of lupus nephritis treatment response, study findings suggest.

Children's Hospital of Philadelphia Pathology and Laboratory Medicine researchers uncovered how killer T cells – called CD8+ T cells – keep fighting inside tumors, where nutrients are scarce and ...

Intralesional nivolumab seems effective for reducing the size of precancerous oral lesions, according to a study presented at the annual meeting of the American Association for Cancer Research, held ...

T-cell engagers (TCEs) drive synthetic antitumor immunity by bypassing endogenous T-cell priming and directly inducing tumor cell killing. In prostate cancer, targeting prostate-restricted antigens ...

Short-term nutritional state can reshape T cell metabolism, with post-meal lipid metabolism enhancing T cell metabolic ...