Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) (EC 1.2.1.12) is an enzyme of about 37 kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy …

Jan 15, 2026 · GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is a Protein Coding gene. Diseases associated with GAPDH include Microcephaly 21, Primary, Autosomal Recessive and …

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has long been recognized as an important enzyme for energy metabolism and the production of ATP and pyruvate through anaerobic glycolysis …

Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity).

Jul 24, 2025 · Beyond its role in energy production, the enzyme GAPDH serves as a complex and sometimes variable benchmark for research and cellular health.

May 14, 2025 · GAPDH exhibits high catalytic efficiency, with a low Km for G3P and NAD⁺, ensuring rapid substrate turnover in glycolysis. It is a soluble, cytoplasmic enzyme but can localize to …

GAPDH as a Control reaction (RT–PCR) assays. In western blot experiments, GAPDH antibodies complementary to their constituent protein are primarily used as eviden e of equal protein loading. …

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a glycolytic enzyme whose role in cell metabolism and homeostasis is well defined, while its function in pathologic processes needs further …

This book will be of great interest to basic scientists, clinicians and students, including molecular and cell biologists, immunologists, pathologists and clinical researchers who are interested in the …

Feb 1, 2011 · Here we review these multifunctional properties of GAPDH, especially linking them to its oligomerization, posttranslational modification, and subcellular localization.