Isogenic human disease models are a family of cells that are selected or engineered to accurately model the genetics of a specific patient population, in vitro.

Jul 1, 2023 · Isogenic refers to a population with essentially identical genes. There are techniques available that can modify the DNA of cells, and this can then be used as a disease model. For …

Jul 19, 2025 · The term “isogenic” describes a population of cells or organisms that are genetically identical. In a laboratory setting, this means a group of cells, often called a cell line, has a …

Dec 5, 2016 · The meaning of ISOGENIC is characterized by essentially identical genes. How to use isogenic in a sentence.

Isogenic strains were sequenced to identify the mutation related to a small colony size.

With genome editing tools such as CRISPR/Cas9, ATCC has created isogenic cell lines with mutants of key oncogenes, which are ideal for elucidating molecular pathways of cancer …

isogenic Pertaining to individuals who are genetically alike, such as identical twins or closely inbred animals. Isogenic individuals are ideal donors to each other of organs for transplantation.

Definition Isogenic refers to a condition where two or more organisms, cells, or genetic materials are genetically identical or have the same genetic constitution.

Apr 15, 2024 · Isogenic refers to organisms with identical genetic makeup, often used in genetics; isogonic pertains to lines of equal magnetic declination on maps, relevant in cartography.

Here, we present an approach to create isogenic pairs of cells that avoids single cell cloning, and screen these pairs with genome-wide CRISPR-Cas9 libraries to generate genetic interaction …