What is Acute Interstitial Nephritis (AIN)? Acute Interstitial Nephritis (AIN) is a condition where the tissues between the kidney tubules suddenly become inflamed and swollen. This sudden swelling prevents the kidneys from filtering waste and excess fluid properly. Common Causes: Medications: The most frequent cause is an allergic reaction to common everyday drugs, especially painkillers (NSAIDs), certain antibiotics, or acid-reflux medicines (PPIs). Infections: Certain bacterial, viral, or fun
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